More study is needed to confirm these results. Irritable bowel syndrome (IBS): In one study, digestive enzymes improved irritable bowel syndrome (IBS) symptoms.A small study found that a supplement containing beta-glucan, inositol, and digestive enzymes improved the quality of life in people with IBD. Inflammatory bowel disease (IBD): IBD includes ulcerative colitis (bowel disease) and Crohn’s disease (inflammation anywhere in the digestive tract, even the mouth).However, more research is needed the study's authors were affiliated with the supplement manufacturer. Functional dyspepsia: A small study suggested that a combination enzyme product containing α-amylase, protease, cellulase, lactase, and lipase reduced indigestion symptoms related to functional dyspepsia.Fermentable carbohydrate digestion: An alpha-galactosidase supplement such as Beano can reduce symptoms like abdominal discomfort and bloating in people who have trouble digesting specific carbohydrates in beans.And they risk worsening symptoms in some cases. However, the benefits of these enzymes are still unclear. Celiac disease: Gluten-degrading enzymes like cysteine proteases, prolyl endopeptidases, and subtilisin have been studied as potential celiac disease treatments.Cancer treatment complications: Some studies suggested OTC enzymes improved the quality of life for people with colorectal cancer.Further study is needed to confirm these findings. However, some studies suggest they may help improve emotional response, behavior, and symptoms such as abdominal pain from lactose intolerance, vomiting, and selective eating. Digestive symptoms in autism spectrum disorder (ASD): Research on digestive enzymes for gut issues in people with ASD is mixed.
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